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[KO Validated] LKB1 Rabbit Polyclonal Antibody (CAB2122)

SKU:
CAB2122
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
  • KO Validated Antibodies 1 Anti-LKB1 Antibody CAB2122KO Validated
  • KO Validated Antibodies 1 Anti-LKB1 Antibody CAB2122KO Validated
  • KO Validated Antibodies 1 Anti-LKB1 Antibody CAB2122KO Validated
  • KO Validated Antibodies 1 Anti-LKB1 Antibody CAB2122KO Validated
  • KO Validated Antibodies 1 Anti-LKB1 Antibody CAB2122KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] LKB1 Rabbit Polyclonal Antibody
SKU:CAB2122
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 134-433 of human LKB1 (NP_000446.1).
Sequence:CGMQ EMLD SVPE KRFP VCQA HGYF CQLI DGLE YLHS QGIV HKDI KPGN LLLT TGGT LKIS DLGV AEAL HPFA ADDT CRTS QGSP AFQP PEIA NGLD TFSG FKVD IWSA GVTL YNIT TGLY PFEG DNIY KLFE NIGK GSYA IPGD CGPP LSDL LKGM LEYE PAKR FSIR QIRQ HSWF RKKH PPAE APVP IPPS PDTK DRWR SMTV VPYL EDLH GADE DEDL FDIE DDII YTQD FTVP GQVP EEEA SHNG QRRG LPKA VCMN GTEA AQLS TKSR AEGR APNP ARKA CSAS SKIR RLSA CKQQ
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:PJS; LKB1; hLKB1
Positive Sample:MCF7,293T,Mouse heart,Rat heart
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Membrane, Mitochondrion, Nucleus.
Calculated MW:49kDa
Observed MW:49-60kDa

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers.

Purification Method:Affinity purification
Gene ID:6794
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using LKB1 Rabbit pAb (CAB2122) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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