STIP1 Rabbit Polyclonal Antibody (CAB14106)
- SKU:
- CAB14106
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | STIP1 Rabbit Polyclonal Antibody |
SKU: | CAB14106 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Monkey |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human STIP1 (NP_006810.1). |
Sequence: | MEQV NELK EKGN KALS VGNI DDAL QCYS EAIK LDPH NHVL YSNR SAAY AKKG DYQK AYED GCKT VDLK PDWG KGYS RKAA ALEF LNRF EEAK RTYE EGLK HEAN NPQL KEGL QNME ARLA ERKF MNPF NMPN LYQK LESD PRTR TLLS DPTY RELI EQLR NKPS DLGT KLQD PRIM TTLS VLLG VDLG SMDE EEEI ATPP PPPP PKKE TKPE PMEE DLPE NKKQ ALKE KELG NDAY KKKD FDTA LKHY DKAK ELDP TNMT YITN QAAV YFEK GDYN KCRE LCEK AIEV GREN REDY RQIA |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521; STIP1 |
Positive Sample: | HeLa,COS-7,COS-1,OVCAR3,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 63kDa |
Observed MW: | 69kDa |
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).
Purification Method: | Affinity purification |
Gene ID: | 10963 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |