STEAP4 Rabbit Polyclonal Antibody (CAB17767)
- SKU:
- CAB17767
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | STEAP4 Rabbit Polyclonal Antibody |
SKU: | CAB17767 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STEAP4 (NP_001192245). |
Sequence: | MEKT CIDA LPLT MNSS EKQE TVCI FGTG DFGR SLGL KMLQ CGYS VVFG SRNP QKTT LLPS GAEV LSYS EAAK KSGI IIIA IHRE HYDF LTEL TEVL NGKI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | TIARP; STAMP2; SchLAH; TNFAIP9; STEAP4 |
Positive Sample: | Rat liver,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Golgi apparatus membrane, Multi-pass membrane protein. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 79689 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |