The STEAP3 Polyclonal Antibody (CAB0683) is a valuable tool for researchers studying the STEAP3 protein, a member of the six-transmembrane epithelial antigen of prostate (STEAP) family. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various applications such as Western blotting. By targeting the STEAP3 protein, researchers can gain insights into its role in cellular processes and potential implications in cancer and other diseases.STEAP3 is a metalloreductase enzyme that plays a critical role in cellular iron metabolism and redox balance. Dysregulation of STEAP3 has been associated with various cancers, making it a potential target for cancer therapies.
By using the STEAP3 Polyclonal Antibody, researchers can further explore the functions and mechanisms of STEAP3 in different cell types and disease contexts, advancing our understanding of its potential as a therapeutic target.Overall, the STEAP3 Polyclonal Antibody is a reliable tool for researchers interested in investigating the functions and implications of the STEAP3 protein in health and disease. Its high specificity and reactivity make it a valuable asset for studies in cancer biology, iron metabolism, and redox signaling pathways.
Product Name:
STEAP3 Rabbit Polyclonal Antibody
SKU:
CAB0683
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human STEAP3 (NP_060704.2).
This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55240
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using STEAP3 Rabbit pAb (CAB0683) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
