The STEAP1 Polyclonal Antibody (CAB17684) is a valuable tool for research involving STEAP1, a cell surface protein associated with iron and copper transport. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in various applications, particularly in Western blotting.STEAP1, also known as six-transmembrane epithelial antigen of the prostate 1, is involved in regulating intracellular iron levels and plays a role in cellular iron homeostasis. Dysregulation of STEAP1 has been linked to various diseases, including cancer and neurodegenerative disorders.
By targeting STEAP1 with this antibody, researchers can gain insights into its function and potential therapeutic applications in these contexts.With its high specificity and reliability, the STEAP1 Polyclonal Antibody (CAB17684) is an essential tool for studying STEAP1 biology and its implications in various disease states. Its use in research can lead to a better understanding of iron metabolism and the development of novel therapeutic strategies targeting STEAP1.
Product Name:
STEAP1 Rabbit Polyclonal Antibody
SKU:
CAB17684
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human STEAP1 (NP_036581.1).
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.
Purification Method:
Affinity purification
Gene ID:
26872
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using STEAP1 Rabbit pAb (CAB17684) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
