STC1 Rabbit Polyclonal Antibody (CAB16976)
- SKU:
- CAB16976
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | STC1 Rabbit Polyclonal Antibody |
SKU: | CAB16976 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-247 of human STC1 (NP_003146.1). |
Sequence: | THEA EQND SVSP RKSR VAAQ NSAE VVRC LNSA LQVG CGAF ACLE NSTC DTDG MYDI CKSF LYSA AKFD TQGK AFVK ESLK CIAN GVTS KVFL AIRR CSTF QRMI AEVQ EECY SKLN VCSI AKRN PEAI TEVV QLPN HFSN RYYN RLVR SLLE CDED TVST IRDS LMEK IGPN MASL FHIL QTDH CAQT HPRA DFNR RRTN EPQK LKVL LRNL RGEE DSPS HIKR TSHE SA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | STC; STC1 |
Positive Sample: | mouse kidney,rat kidney |
Cellular Localization: | Secreted. |
Calculated MW: | 28kDa |
Observed MW: | 27kDa |
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
Purification Method: | Affinity purification |
Gene ID: | 6781 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |