The STC1 Polyclonal Antibody (CAB16976) is a valuable tool for studying STC1, a protein associated with various physiological processes such as cell proliferation, differentiation, and migration. This antibody is produced in rabbits and has been validated for use in Western blot applications, providing researchers with a reliable tool for detecting and analyzing STC1 levels in different cell types.STC1, also known as stanniocalcin 1, is a secreted glycoprotein that has been linked to diverse functions including calcium and phosphate homeostasis, angiogenesis, and cell survival.
Its role in cancer development, cardiovascular disease, and metabolic disorders makes it a promising target for further investigation in biomedical research.By using the STC1 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying STC1's biological functions and its potential as a therapeutic target for various diseases. This antibody is a valuable tool for studies in cell biology, cancer research, and endocrinology, providing a versatile and reliable option for scientists looking to explore the role of STC1 in health and disease.
Product Name:
STC1 Rabbit Polyclonal Antibody
SKU:
CAB16976
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-247 of human STC1 (NP_003146.1).
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
Purification Method:
Affinity purification
Gene ID:
6781
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STC1 antibody (CAB16976) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
