Anti-Staufen Antibody (CAB4619)
- SKU:
- CAB4619
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PPP1R150
- STAU
Description
Anti-Staufen Antibody (CAB4619)
The Staufen Rabbit Monoclonal Antibody (CAB4619) is a high-quality research tool designed for the detection of Staufen protein in various cell types. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in Western blot applications. Staufen is a key protein involved in the regulation of mRNA transport and localization within cells, playing a critical role in post-transcriptional gene expression. By targeting Staufen, researchers can study its function in processes such as neuronal development, synaptic plasticity, and RNA metabolism.
With its high reactivity and specificity, the Staufen Rabbit Monoclonal Antibody is ideal for studies in neurobiology, molecular biology, and developmental biology. By enabling the detection and analysis of Staufen protein, this antibody facilitates a better understanding of its role in cellular processes and its potential implications in diseases like neurodegenerative disorders and cancer.
| Product Name: | Staufen Rabbit mAb |
| Product Code: | CAB4619 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | PPP1R150, STAU |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Staufen |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human Staufen |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6780 |
| Uniprot: | O95793 |
| Cellular Location: | Cytoplasm, Rough endoplasmic reticulum |
| Calculated MW: | 55kDa |
| Observed MW: | 63KDa |
| UniProt Protein Function: | STAU: Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 20q13.1 Cellular Component: microtubule associated complex; cell soma; rough endoplasmic reticulum; membrane; endoplasmic reticulum; stress granule; dendrite; cytoplasm Molecular Function:protein binding; double-stranded RNA binding; protein phosphatase 1 binding Biological Process: intracellular mRNA localization; positive regulation of viral genome replication; positive regulation of viral protein levels in host cell |
| UniProt Code: | O95793 |
| NCBI GenInfo Identifier: | 90185286 |
| NCBI Gene ID: | |
| NCBI Accession: | O95793.2 |
| Molecular Weight: | 55kDa |
| NCBI Full Name: | Double-stranded RNA-binding protein Staufen homolog 1 |
| UniProt Protein Name: | Double-stranded RNA-binding protein Staufen homolog 1 |
| Protein Family: | Maternal effect protein staufen |
| UniProt Gene Name: | STAU1Â Â |
| UniProt Entry Name: | STAU1_HUMAN |
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