The STAU2 Polyclonal Antibody (CAB14117) is a valuable tool for researchers studying STAU2, a protein involved in post-transcriptional regulation of gene expression. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the STAU2 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in molecular biology and RNA metabolism.STAU2 plays a crucial role in RNA localization and stability, particularly in the regulation of mRNA decay and translation.
Its involvement in post-transcriptional gene regulation makes it a key player in processes like cell differentiation and development. Research into STAU2 is relevant to understanding diseases related to RNA dysregulation, such as neurological disorders and certain types of cancer. By studying STAU2 with this antibody, researchers can further unravel the complexities of post-transcriptional control mechanisms and potentially identify new therapeutic targets.
Product Name:
STAU2 Rabbit Polyclonal Antibody
SKU:
CAB14117
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human STAU2 (NP_001157852.1).
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
27067
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STAU2 antibody (CAB14117) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
