Staufen Rabbit Polyclonal Antibody (CAB4131)
- SKU:
- CAB4131
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | Staufen Rabbit Polyclonal Antibody |
SKU: | CAB4131 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 426-577 of human Staufen (NP_059347.2). |
Sequence: | QAVG VSQG HHTK DFTR AAPN PAKA TVTA MIAR ELLY GGTS PTAE TILK NNIS SGHV PHGP LTRP SEQL DYLS RVQG FQVE YKDF PKNN KNEF VSLI NCSS QPPL ISHG IGKD VESC HDMA ALNI LKLL SELD QQST EMPR TGNG PMSV CGRC |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:100 |
Synonyms: | STAU; PPP1R150; Staufen |
Positive Sample: | Mouse liver,Mouse brain,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Rough endoplasmic reticulum. |
Calculated MW: | 63kDa |
Observed MW: | 63kDa |
Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation.
Purification Method: | Affinity purification |
Gene ID: | 6780 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |