The Stathmin Polyclonal Antibody (CAB2176) is an essential tool for researchers studying stathmin, a key regulator of microtubule dynamics and cell division. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to stathmin protein, allowing for accurate detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.Stathmin, also known as oncoprotein 18, plays a crucial role in cell proliferation and cytoskeleton organization, making it a target of interest in cancer research.
Its overexpression has been linked to tumor progression and metastasis, highlighting its potential as a therapeutic target. By utilizing the Stathmin Polyclonal Antibody, researchers can gain insights into the mechanisms underlying stathmin function and its implications in cancer development, paving the way for novel treatment strategies targeting this protein.
Product Name:
Stathmin 1 Rabbit Polyclonal Antibody
SKU:
CAB2176
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Stathmin 1 (NP_005554.1).
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3925
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Stathmin 1 Rabbit pAb (CAB2176) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
