STAT4 Rabbit Monoclonal Antibody (CAB4523)
- SKU:
- CAB4523
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SLEB11
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | STAT4 Rabbit Monoclonal Antibody |
SKU: | CAB4523 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 649-748 of human STAT4 (NP_003142.1). |
Sequence: | MAEN IPEN PLKY LYPD IPKD KAFG KHYS SQPC EVSR PTER GDKG YVPS VFIP ISTI RSDS TEPH SPSD LLPM SPSV YAVL RENL SPTT IETA MKSP YSAE |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | SLEB11; STAT4 |
Positive Sample: | HeLa,PC-3,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 86kDa |
Observed MW: | 86kDa |
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Purification Method: | Affinity purification |
Gene ID: | 6775 |
Clone Number: | ARC1071 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |