STAT4 Rabbit Polyclonal Antibody (CAB6991)
- SKU:
- CAB6991
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | STAT4 Rabbit Polyclonal Antibody |
SKU: | CAB6991 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 569-748 of human STAT4 (NP_003142.1). |
Sequence: | WIDG YVMG FVSK EKER LLLK DKMP GTFL LRFS ESHL GGIT FTWV DHSE SGEV RFHS VEPY NKGR LSAL PFAD ILRD YKVI MAEN IPEN PLKY LYPD IPKD KAFG KHYS SQPC EVSR PTER GDKG YVPS VFIP ISTI RSDS TEPH SPSD LLPM SPSV YAVL RENL SPTT IETA MKSP YSAE |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | SLEB11; STAT4 |
Positive Sample: | NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 86kDa |
Observed MW: | 76kDa |
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Purification Method: | Affinity purification |
Gene ID: | 6775 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |