The STAT2 Rabbit Monoclonal Antibody (CAB3588) is a valuable tool for researchers studying the signal transducer and activator of transcription 2 (STAT2) protein. This antibody, raised in rabbits, is highly specific for detecting STAT2 in human samples and is validated for use in a variety of applications, including Western blotting.STAT2 is a key protein in the JAK-STAT signaling pathway, playing a crucial role in regulating immune responses and cell growth. Dysregulation of STAT2 has been implicated in various diseases, including cancer and autoimmune disorders.
By using the STAT2 Rabbit Monoclonal Antibody, researchers can accurately detect and analyze STAT2 expression in different cell types, providing valuable insights for immunology and cancer research studies.With its high reactivity and specificity, the STAT2 Rabbit Monoclonal Antibody is a reliable tool for investigating the functions and mechanisms of STAT2, ultimately contributing to the development of new therapies and treatments targeting diseases associated with STAT2 dysregulation.
Product Name:
STAT2 Rabbit Monoclonal Antibody
SKU:
CAB3588
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 550-706 of human STAT2 (NP_005410.1).
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44.
Purification Method:
Affinity purification
Gene ID:
6773
Clone Number:
ARC51796
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat liver, using STAT2 antibody (CAB3588) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
