STAT2 Rabbit Polyclonal Antibody (CAB14995)
- SKU:
- CAB14995
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | STAT2 Rabbit Polyclonal Antibody |
SKU: | CAB14995 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-706 of human STAT2 (NP_005410.1). |
Sequence: | KLPF WTWL DKIL ELVH DHLK DLWN DGRI MGFV SRSQ ERRL LKKT MSGT FLLR FSES SEGG ITCS WVEH QDDD KVLI YSVQ PYTK EVLQ SLPL TEII RHYQ LLTE ENIP ENPL RFLY PRIP RDEA FGCY YQEK VNLQ ERRK YLKH RLIV VSNR QVDE L |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Synonyms: | P113; IMD44; ISGF-3; PTORCH3; STAT113; STAT2 |
Positive Sample: | A-549,A-431,U-937,Mouse brain,Rat liver,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 98kDa |
Observed MW: | 113kDa |
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44.
Purification Method: | Affinity purification |
Gene ID: | 6773 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |