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STAT2 Monoclonal Antibody

SKU:
CAB23472
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

STAT2 Monoclonal Antibody (CAB23472)

The STAT2 Monoclonal Antibody is a valuable tool for researchers studying the signal transducer and activator of transcription 2 (STAT2) protein. This antibody, derived from mouse cells, is highly specific in recognizing and binding to STAT2 in human samples. It has been validated for use in various applications, including Western blot and immunohistochemistry, allowing for accurate detection and analysis of STAT2 protein levels in different cell types.STAT2 is a key player in the interferon signaling pathway, regulating the expression of genes involved in antiviral responses and immune defense.

Dysregulation of STAT2 function has been implicated in various diseases, including viral infections and autoimmune disorders. By targeting STAT2, researchers can better understand the mechanisms underlying these diseases and potentially develop targeted therapies to modulate immune responses.Overall, the STAT2 Monoclonal Antibody provides researchers with a reliable tool to investigate the role of STAT2 in health and disease, making it an essential reagent in the fields of immunology and virology research.

Product Name:STAT2 Monoclonal Antibody
Product Code:CAB23472
Reactivity:Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC51803
Reactivity:Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Mouse brain, Rat brain
Cellular Location:Cytoplasm, Nucleus

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44.

Immunogen:Recombinant protein of human STAT2.
Sequence:Email for sequence
Synonyms:P113, IMD44, ISGF-3, PTORCH3, STAT113
Calculated MW:98kDa
Observed MW:97kDa/113kDa

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