STAT1 Rabbit Polyclonal Antibody (CAB0027)
- SKU:
- CAB0027
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Product Name: | STAT1 Rabbit Polyclonal Antibody |
| SKU: | CAB0027 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 513-712 of human STAT1 (NP_009330.1). |
| Sequence: | GLNV DQLN MLGE KLLG PNAS PDGL IPWT RFCK ENIN DKNF PFWL WIES ILEL IKKH LLPL WNDG CIMG FISK ERER ALLK DQQP GTFL LRFS ESSR EGAI TFTW VERS QNGG EPDF HAVE PYTK KELS AVTF PDII RNYK VMAA ENIP ENPL KYLY PNID KDHA FGKY YSRP KEAP EPME LDGP KGTG YIKT ELIS VSEV |
| Tested Applications: | WB IHC-P ELISA |
| Recommended Dilution: | WB,1:2000 - 1:6000 IHC-P,1:50 - 1:200 |
| Synonyms: | CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91; STAT1 |
| Positive Sample: | HT-29,Mouse kidney,Mouse heart |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Nucleus. |
| Calculated MW: | 87kDa |
| Observed MW: | 84kDa |
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C.
| Purification Method: | Affinity purification |
| Gene ID: | 6772 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using STAT1 Rabbit pAb (CAB0027) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s. |
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