UniProt Protein Function: | STARD8: Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GAPs, Rac/Rho; GAPs Chromosomal Location of Human Ortholog: Xq13.1 Cellular Component: cytosol Molecular Function:GTPase activator activity Biological Process: regulation of small GTPase mediated signal transduction |
NCBI Summary: | This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor. [provided by RefSeq, Mar 2010] |
UniProt Code: | Q92502 |
NCBI GenInfo Identifier: | 90110072 |
NCBI Gene ID: | 9754 |
NCBI Accession: | Q92502.2 |
UniProt Secondary Accession: | Q92502,Q5JST0, Q68DG7, A8K6T2, D3DVT9, |
UniProt Related Accession: | Q92502 |
Molecular Weight: | 121,749 Da |
NCBI Full Name: | StAR-related lipid transfer protein 8 |
NCBI Synonym Full Names: | StAR related lipid transfer domain containing 8 |
NCBI Official Symbol: | STARD8Â Â |
NCBI Official Synonym Symbols: | DLC3; ARHGAP38; STARTGAP3Â Â |
NCBI Protein Information: | stAR-related lipid transfer protein 8 |
UniProt Protein Name: | StAR-related lipid transfer protein 8 |
UniProt Synonym Protein Names: | Deleted in liver cancer 3 protein; DLC-3; START domain-containing protein 8; StARD8; START-GAP3 |
Protein Family: | StAR-related lipid transfer protein |
UniProt Gene Name: | STARD8Â Â |
UniProt Entry Name: | STAR8_HUMAN |