The STARD3NL Polyclonal Antibody (CAB16579) is a valuable tool for researchers studying STARD3NL, a protein involved in lipid transport and metabolism within cells. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to STARD3NL, it enables the detection and analysis of this protein in various cell types, making it ideal for studies in cellular biology and lipid metabolism research.STARD3NL is a member of the STARD protein family and is known to play a crucial role in the intracellular trafficking of cholesterol and other lipids.
Understanding the functions of STARD3NL is important for gaining insights into cellular lipid homeostasis and its implications in various diseases such as cardiovascular disorders and metabolic syndromes. Researchers can use this antibody to explore the expression and localization of STARD3NL in different cellular contexts, paving the way for new discoveries in lipid biology and potential therapeutic targets.
Product Name:
STARD3NL Rabbit Polyclonal Antibody
SKU:
CAB16579
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 185-234 of human STARD3NL (NP_114405.1).
Sequence:
RLLI VQDA SERA ALIP GGLS DGQF YSPP ESEA GSEE AEEK QDSE KPLL EL
Tested Applications:
WBIHC-PELISA
Recommended Dilution:
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:
MENTHO; STARD3NL
Positive Sample:
HeLa,293T,MCF7,Mouse testis
Conjugate:
Unconjugated
Cellular Localization:
Late endosome membrane, Multi-pass membrane protein.
Calculated MW:
27kDa
Observed MW:
26kDa
This gene encodes a late-endosomal protein that contains a conserved MENTAL (MLN64 N-terminal) domain. The encoded protein binds cholesterol molecules and may play a role in endosomal cholesterol transport through interactions with metastatic lymph node protein 64 (MLN64).
Purification Method:
Affinity purification
Gene ID:
83930
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using STARD3NL Rabbit pAb (CAB16579) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.