The STARD3 Polyclonal Antibody (CAB7776) is a valuable tool for researchers studying STARD3, a protein involved in lipid transport and intracellular cholesterol metabolism. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the STARD3 protein, this antibody allows for the detection and analysis of STARD3 expression in a variety of cell types, making it an ideal choice for studies in cell biology, lipid metabolism, and cholesterol homeostasis.STARD3, also known as StAR-related lipid transfer domain containing 3, plays a crucial role in the intracellular trafficking of cholesterol and other lipids.
Dysregulation of STARD3 has been implicated in various diseases, including cardiovascular disorders and metabolic conditions. Research into the function of STARD3 is essential for understanding its role in lipid metabolism and developing potential therapeutic interventions for related disorders.Overall, the STARD3 Polyclonal Antibody is a valuable tool for researchers investigating the role of STARD3 in lipid transport and cholesterol metabolism, with potential implications for the development of novel treatments for lipid-related diseases.
Product Name:
STARD3 Rabbit Polyclonal Antibody
SKU:
CAB7776
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-445 of human STARD3 (NP_006795.3).
Late endosome membrane, Multi-pass membrane protein.
Calculated MW:
51kDa
Observed MW:
45kDa
This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10948
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STARD3 antibody (CAB7776) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
