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STARD13 Antibody (PACO59573)

SKU:
PACO59573
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339

Description

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STARD13 Antibody (PACO59573)

The STARD13 Polyclonal Antibody (PAC059573) is a vital tool for researchers studying the STARD13 protein, which is involved in cellular processes such as lipid metabolism and membrane trafficking. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it a reliable choice for Western blot applications.STARD13, also known as StAR-related lipid transfer protein 13, plays a crucial role in regulating intracellular lipid transport and maintaining proper cell function. Dysregulation of STARD13 has been linked to various diseases, including cancer and metabolic disorders, making it a promising target for further investigation.

By using the STARD13 Polyclonal Antibody, researchers can effectively detect and analyze STARD13 expression in different cell types, advancing our understanding of its role in cellular physiology. This antibody is a valuable tool for studies in molecular biology, biochemistry, and oncology, providing insights that may lead to the development of novel therapeutic strategies targeting STARD13-related pathways.

Antibody Name:STARD13 Antibody (PACO59573)
Antibody SKU:PACO59573
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IF
Recommended Dilutions:ELISA:1:2000-1:10000, IF:1:200-1:500
Species Reactivity:Human
Immunogen:Recombinant Human StAR-related lipid transfer protein 13 protein (516-679AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunofluorescence staining of MCF-7 cells with PACO59573 at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
Synonyms:StAR-related lipid transfer protein 13 (46H23.2) (Deleted in liver cancer 2 protein) (DLC-2) (Rho GTPase-activating protein) (START domain-containing protein 13) (StARD13), STARD13, DLC2 GT650
UniProt Protein Function:GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
UniProt Protein Details:
NCBI Summary:This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
UniProt Code:Q9Y3M8
NCBI GenInfo Identifier:343478259
NCBI Gene ID:90627
NCBI Accession:NP_001230395.1
UniProt Secondary Accession:Q9Y3M8,Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1 A2A309, A2A310
UniProt Related Accession:Q9Y3M8
Molecular Weight:76,367 Da
NCBI Full Name:stAR-related lipid transfer protein 13 isoform 5
NCBI Synonym Full Names:StAR related lipid transfer domain containing 13
NCBI Official Symbol:STARD13  
NCBI Official Synonym Symbols:DLC2; GT650; ARHGAP37; LINC00464  
NCBI Protein Information:stAR-related lipid transfer protein 13
UniProt Protein Name:StAR-related lipid transfer protein 13
UniProt Synonym Protein Names:46H23.2; Deleted in liver cancer 2 protein; DLC-2; Rho GTPase-activating protein; START domain-containing protein 13; StARD13
Protein Family:
UniProt Gene Name:STARD13  
UniProt Entry Name:
Antibodies
STARD13 Antibody (PACO05676)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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