| UniProt Protein Function: | GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q9Y3M8 |
| NCBI GenInfo Identifier: | 343478259 |
| NCBI Gene ID: | 90627 |
| NCBI Accession: | NP_001230395.1 |
| UniProt Secondary Accession: | Q9Y3M8,Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1 A2A309, A2A310 |
| UniProt Related Accession: | Q9Y3M8 |
| Molecular Weight: | 76,367 Da |
| NCBI Full Name: | stAR-related lipid transfer protein 13 isoform 5 |
| NCBI Synonym Full Names: | StAR related lipid transfer domain containing 13 |
| NCBI Official Symbol: | STARD13Â Â |
| NCBI Official Synonym Symbols: | DLC2; GT650; ARHGAP37; LINC00464Â Â |
| NCBI Protein Information: | stAR-related lipid transfer protein 13 |
| UniProt Protein Name: | StAR-related lipid transfer protein 13 |
| UniProt Synonym Protein Names: | 46H23.2; Deleted in liver cancer 2 protein; DLC-2; Rho GTPase-activating protein; START domain-containing protein 13; StARD13 |
| Protein Family: | |
| UniProt Gene Name: | STARD13Â Â |
| UniProt Entry Name: | |
