The STAR Polyclonal Antibody (CAB16432) is a powerful tool for researchers studying the STAR protein, a key regulator of RNA translation and gene expression. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the STAR protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and gene regulation studies.The STAR protein, also known as Signal Transduction Activator of RNA, plays a crucial role in controlling the translation of specific mRNAs, ultimately influencing protein synthesis and cellular function.
Understanding the function and regulation of the STAR protein is essential for unraveling the complexities of gene expression and its impact on various cellular processes. The STAR Polyclonal Antibody provides researchers with a reliable tool to further explore the mechanisms underlying gene regulation and potential therapeutic targets for diseases related to abnormal RNA translation.
Product Name:
STAR Rabbit Polyclonal Antibody
SKU:
CAB16432
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 64-285 of human StAR (NP_000340.2).
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
Purification Method:
Affinity purification
Gene ID:
6770
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using StAR antibody (CAB16432) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
