The Stanniocalcin-1 Polyclonal Antibody (CAB6755) is a valuable tool for researchers studying the protein Stanniocalcin-1, which is involved in a wide range of physiological processes including calcium and phosphate homeostasis, cell proliferation, and angiogenesis. This antibody, produced in rabbits, is highly specific and shows strong reactivity with human samples.Validated for use in Western blot applications, the Stanniocalcin-1 Polyclonal Antibody enables researchers to detect and analyze the Stanniocalcin-1 protein in various cell types, making it ideal for studies in endocrinology, cancer research, and developmental biology.
Stanniocalcin-1 has been implicated in various diseases including cancer, cardiovascular disorders, and metabolic diseases, making it a promising target for therapeutic intervention. Understanding the role of Stanniocalcin-1 in these conditions may lead to the development of novel treatments that target this protein. Overall, the Stanniocalcin-1 Polyclonal Antibody is a reliable tool for researchers looking to expand their understanding of Stanniocalcin-1 and its involvement in various physiological and pathological processes.
Product Name:
STC1 Rabbit Polyclonal Antibody
SKU:
CAB6755
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-247 of human STC1 (NP_003146.1).
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
Purification Method:
Affinity purification
Gene ID:
6781
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse lung, using STC1 Antibody (CAB6755) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
