The STAMBP Polyclonal Antibody (CAB7065) is a high-quality antibody designed for research on STAMBP, a protein involved in the regulation of endocytosis and intracellular trafficking. This antibody is produced by immunizing rabbits and is highly reactive with human samples, making it suitable for a variety of experimental applications.STAMBP is a critical regulator of endosomal sorting and recycling, playing a key role in maintaining cellular homeostasis and proper functioning of the endocytic pathway.
Dysregulation of STAMBP has been linked to various diseases, including cancer and neurodegenerative disorders, making it an important target for further study.This antibody has been validated for use in Western blotting applications, allowing for the detection and analysis of STAMBP in different cell types and tissues. Its specificity and sensitivity make it an ideal tool for researchers interested in investigating the cellular functions of STAMBP and its potential implications in disease pathology.
Product Name:
STAMBP Rabbit Polyclonal Antibody
SKU:
CAB7065
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-270 of human STAMBP (NP_998787.1).
Cytoplasm, Early endosome, Membrane, Nucleus, Peripheral membrane protein.
Calculated MW:
48kDa
Observed MW:
48kDa
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10617
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using STAMBP Rabbit pAb (CAB7065) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
