STAM2 Rabbit Polyclonal Antibody (CAB7058)
- SKU:
- CAB7058
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | STAM2 Rabbit Polyclonal Antibody |
SKU: | CAB7058 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human STAM2 (NP_005834.4). |
Sequence: | KLHP PAHY PPAS SGVP MQTY PVQS HGGN YMGQ SIHQ VTVA QSYS LGPD QIGP LRSL PPNV NSSV TAQP AQTS YLST GQDT VSNP TYMN QNSN LQSA TGTT AYTQ QMGM SVDM SSYQ NTTS NLPQ LAGF PVTV PAHP VAQQ HTNY HQQP LL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | Hbp; STAM2A; STAM2B; STAM2 |
Positive Sample: | MCF7,HepG2,OVCAR3,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic side, Early endosome membrane, Peripheral membrane protein. |
Calculated MW: | 58kDa |
Observed MW: | 70kDa |
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
Purification Method: | Affinity purification |
Gene ID: | 10254 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |