The STAM2 Polyclonal Antibody (CAB7058) is a valuable tool for researchers studying Signal Transducing Adaptor Molecule 2 (STAM2), a protein involved in intracellular signaling pathways and endosomal trafficking. This antibody, produced in rabbits, has been extensively validated for use in Western blot applications and is highly reactive with human samples.STAM2 plays a crucial role in regulating cellular processes such as receptor trafficking, cell proliferation, and cell survival. By targeting STAM2 with this antibody, researchers can effectively analyze the expression and function of the protein in various cell types, providing insights into its involvement in physiological and pathological conditions.
With its ability to specifically bind to STAM2, the CAB7058 antibody is an excellent tool for investigations in cell biology, molecular biology, and cancer research. Understanding the role of STAM2 in intracellular signaling mechanisms can lead to potential therapeutic strategies targeting diseases such as cancer, neurodegenerative disorders, and viral infections. Unlock the potential of STAM2 research with the reliable and sensitive CAB7058 Polyclonal Antibody.
Product Name:
STAM2 Rabbit Polyclonal Antibody
SKU:
CAB7058
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human STAM2 (NP_005834.4).
Cytoplasm, Cytoplasmic side, Early endosome membrane, Peripheral membrane protein.
Calculated MW:
58kDa
Observed MW:
70kDa
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
Purification Method:
Affinity purification
Gene ID:
10254
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STAM2 antibody (CAB7058) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
