The STAC3 Polyclonal Antibody (PAC012498) is a valuable tool for researchers studying STAC3, a key protein involved in muscle function and calcium signaling pathways. This antibody, produced in rabbits, is highly specific for STAC3 and has been validated for use in Western blot applications, allowing for the detection and analysis of STAC3 in a variety of cell types.STAC3 is essential for the proper functioning of skeletal muscle, as it plays a crucial role in facilitating the interaction between the dihydropyridine receptor (DHPR) and the ryanodine receptor (RyR) in the muscle cell membrane.
This interaction is vital for the release of calcium ions, which are necessary for muscle contraction. Dysfunction of STAC3 has been linked to muscle disorders, making it a target of interest for research in muscle physiology and disease.By studying STAC3 and its role in muscle function, researchers can gain a better understanding of muscle disorders and potentially identify new therapeutic targets for conditions such as muscle weakness and paralysis. The STAC3 Polyclonal Antibody is a valuable tool for investigating the function of STAC3 and its implications in muscle health and disease.
The protein encoded by this gene is a component of the excitation-contraction coupling machinery of muscles. This protein is a member of the Stac gene family and contains an N-terminal cysteine-rich domain and two SH3 domains. Mutations in this gene are a cause of Native American myopathy. [provided by RefSeq, Nov 2013]
