The STAC2 Polyclonal Antibody (PAC023482) is a valuable tool for researchers studying STAC2, a protein involved in the regulation of skeletal muscle development and function. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the STAC2 protein, this antibody enables researchers to detect and analyze STAC2 expression in various cell types, making it an essential tool for studies in muscle biology and related fields.STAC2 is a critical regulator of excitation-contraction coupling in skeletal muscle cells, playing a key role in the communication between the voltage-sensing dihydropyridine receptor (DHPR) and the calcium release channel ryanodine receptor (RyR).
Dysregulation of STAC2 has been linked to muscle disorders such as myotonic dystrophy and muscular dystrophy, making it an attractive target for therapeutic interventions aimed at improving muscle function and overall health.By investigating the function and expression of STAC2, researchers can gain valuable insights into the mechanisms underlying muscle development, contraction, and disease. The STAC2 Polyclonal Antibody provides a reliable tool for studying STAC2 and its implications in muscle biology, paving the way for potential therapeutic strategies targeting muscle disorders.
Antibody Name:
STAC2 Antibody (PACO23482)
Antibody SKU:
PACO23482
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human STAC2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using STAC2 antibody.
Western blot analysis of extracts from cos-7 cells (Lane 2), using STAC2 antiobdy. The lane on the left is treated with synthesized peptide.
Synonyms:
24b2; 24b2/STAC2; SH3 and cysteine rich domain 2;
UniProt Protein Function:
STAC2: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Lipid-bindingChromosomal Location of Human Ortholog: 17q12Molecular Function: metal ion binding
