The STAC Polyclonal Antibody (CAB15319) is a valuable tool for researchers studying the STAC protein, a crucial regulator of muscle function and calcium signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By binding to the STAC protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential asset for studies in muscle biology and disease mechanisms.The STAC protein, also known as SH3 and cysteine-rich domain-containing protein, is involved in the excitation-contraction coupling process in skeletal muscle, playing a key role in calcium release and muscle contraction.
Dysregulation of the STAC protein has been linked to muscle disorders and diseases such as muscular dystrophy and myopathy, highlighting its significance in muscle physiology and pathology.Research into the functions and mechanisms of the STAC protein is essential for uncovering novel therapeutic targets and strategies for treating muscle-related disorders. By utilizing the STAC Polyclonal Antibody, researchers can gain valuable insights into the role of the STAC protein in health and disease, ultimately advancing our understanding of muscle function and potential therapeutic interventions.
Product Name:
STAC Rabbit Polyclonal Antibody
SKU:
CAB15319
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 153-402 of human STAC (NP_003140.1).
Predicted to enable transmembrane transporter binding activity. Predicted to be involved in positive regulation of protein localization to plasma membrane; positive regulation of voltage-gated calcium channel activity; and skeletal muscle contraction. Predicted to act upstream of or within cellular response to heat; muscle contraction; and regulation of voltage-gated calcium channel activity. Predicted to be located in T-tubule. Predicted to be extrinsic component of cytoplasmic side of plasma membrane.
Purification Method:
Affinity purification
Gene ID:
6769
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using STAC Rabbit pAb (CAB15319) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
