The ST8SIA2 Polyclonal Antibody (CAB7748) is a valuable tool for researchers studying ST8SIA2, a critical enzyme involved in the synthesis of polysialic acid. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ST8SIA2 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for investigations in neuroscience, developmental biology, and cancer research.ST8SIA2 plays a crucial role in cell adhesion and migration processes, particularly in the developing nervous system.
Dysregulation of ST8SIA2 has been implicated in various disorders, including neurological conditions and certain types of cancer. By studying the function of ST8SIA2, researchers can uncover important insights into disease mechanisms and potentially identify new therapeutic targets for intervention.Overall, the ST8SIA2 Polyclonal Antibody is a powerful tool for researchers seeking to further explore the roles of ST8SIA2 in physiological and pathological processes, ultimately contributing to advancements in scientific understanding and potential drug development efforts.
Product Name:
ST8SIA2 Rabbit Polyclonal Antibody
SKU:
CAB7748
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-160 of human ST8SIA2 (NP_006002.1).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
42kDa
Observed MW:
42kDa
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29.
Purification Method:
Affinity purification
Gene ID:
8128
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ST8SIA2 antibody (CAB7748) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
