The ST7L Polyclonal Antibody (PAC012495) is a valuable tool for researchers studying ST7L, a member of the ST7 tumor suppressor gene family known for its role in cell growth regulation. This antibody is raised in rabbits and is highly specific for human samples, making it an ideal choice for Western blot applications. By targeting the ST7L protein, this antibody allows for the detection and analysis of ST7L expression in various cell types, providing valuable insights for studies in cancer and developmental biology.ST7L is a key player in cellular processes such as apoptosis, cell cycle regulation, and cell migration, making it a promising target for cancer research and potential therapeutic interventions.
Understanding the function and regulation of ST7L is essential for unraveling its potential as a tumor suppressor and its implications in cancer progression. By using the ST7L Polyclonal Antibody, researchers can further elucidate the molecular mechanisms underlying ST7L's tumor suppressor activity and its impact on cell proliferation and survival.
suppression of tumorigenicity 7 like;ST7L;FAM4B;FLJ11657;FLJ20284;ST7R;STLR ;
UniProt Protein Function:
ST7L: identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011]Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 1p13.2Biological Process: negative regulation of cell growth
UniProt Protein Details:
NCBI Summary:
This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011]