The ST6GALNAC6 Polyclonal Antibody (PACO39526) is a valuable tool for research involving the ST6GALNAC6 protein, a member of the sialyltransferase family that is involved in the biosynthesis of sialyl-Tn antigen. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the ST6GALNAC6 protein, this antibody allows for the detection and analysis of this important glycosyltransferase in various cell types, making it an essential tool for studies in glycobiology and cancer research.
ST6GALNAC6 is known to play a role in the glycosylation of proteins, which can have implications in cell adhesion, signaling, and immune response. Dysregulation of ST6GALNAC6 has been linked to certain types of cancer, making it a potential target for therapeutic intervention. By studying the function of ST6GALNAC6, researchers can gain valuable insights into the role of protein glycosylation in disease progression and potentially identify new targets for drug development aimed at combating cancer and other glycosylation-related disorders.
Antibody Name:
ST6GALNAC6 Antibody (PACO39526)
Antibody SKU:
PACO39526
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 protein (65-333AA)
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39526 at dilution of 1:100.
Background:
Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participates in the synthesis of disialyl Lewis a (Le(a)).
