The ST6GALNAC5 Polyclonal Antibody (CAB17782) is a valuable tool for researchers studying the ST6GALNAC5 protein, which is involved in the glycosylation of mucins and plays a role in cancer progression and metastasis. This rabbit polyclonal antibody is highly specific and sensitive for detecting ST6GALNAC5 in human samples, making it an ideal choice for Western blot applications. By targeting the ST6GALNAC5 protein, researchers can gain insights into its function in various cell types, particularly in studies related to cancer biology and metastasis.
ST6GALNAC5, a member of the sialyltransferase family, is a key enzyme that adds sialic acid residues to glycoproteins and glycolipids. Aberrant expression of ST6GALNAC5 has been linked to cancer progression, metastasis, and poor patient prognosis, making it a promising target for cancer research and drug development. Understanding the role of ST6GALNAC5 in glycosylation processes and cancer biology is essential for developing targeted therapies and diagnostic tools in the fight against cancer.
Product Name:
ST6GALNAC5 Rabbit Polyclonal Antibody
SKU:
CAB17782
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-336 of human ST6GALNAC5 (NP_112227.1).
The protein encoded by this gene is a Golgi type II transmembrane glycosyltransferase. The encoded protein catalyzes the transfer of sialic acid to cell surface proteins to modulate cell-cell interactions. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
81849
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ST6GALNAC5 Rabbit pAb (CAB17782) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.