ST6GALNAC4 Rabbit Polyclonal Antibody (CAB12880)
- SKU:
- CAB12880
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | ST6GALNAC4 Rabbit Polyclonal Antibody |
SKU: | CAB12880 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human ST6GALNAC4 (NP_778204.1). |
Sequence: | TLRV VSHT SVPL LLRN YSHY FQKA RDTL YMVW GQGR HMDR VLGG RTYR TLLQ LTRM YPGL QVYT FTER MMAY CDQI FQDE TGKN RRQS GSF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | IV; SIAT3C; SIAT7D; SIAT3-C; SIAT7-D; ST6GalNAc; ST6GALNACIV; ST6GALNAC4 |
Positive Sample: | A-549,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus membrane, Single-pass type II membrane protein. |
Calculated MW: | 34kDa |
Observed MW: | 34kDa |
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. Readthrough transcripts exist for this gene and the downstream ST6GALNAC6 gene.
Purification Method: | Affinity purification |
Gene ID: | 27090 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |