The ST6GALNAC2 Polyclonal Antibody (CAB17618) is a valuable tool for researchers studying ST6GALNAC2, an enzyme involved in the synthesis of sialyl-Tn antigen, which is overexpressed in many cancer types. This rabbit-derived antibody is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ST6GALNAC2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component in studies focused on cancer biology and immunotherapy.The ST6GALNAC2 enzyme plays a crucial role in tumor progression and immune evasion, making it a promising target for cancer therapy.
Its aberrant expression has been linked to metastasis and poor patient outcomes in various types of cancer. Understanding the function and regulation of ST6GALNAC2 is vital for developing targeted therapies that can disrupt tumor growth and enhance immune responses against cancer cells. Researchers in the fields of oncology and immunology will benefit greatly from the use of this antibody in their investigations.
Product Name:
ST6GALNAC2 Rabbit Polyclonal Antibody
SKU:
CAB17618
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human ST6GALNAC2 (NP_006447.2).
ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).
Purification Method:
Affinity purification
Gene ID:
10610
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ST6GALNAC2 Rabbit pAb (CAB17618) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
