The ST3GAL4 Polyclonal Antibody (CAB6309) is a valuable tool for researchers studying the ST3GAL4 protein, which plays a crucial role in synthesizing cell surface carbohydrate structures. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ST3GAL4 protein, the antibody enables accurate detection and analysis in a variety of cell types, making it an essential component in studies focused on glycobiology and cellular signaling pathways.ST3GAL4 is a key enzyme involved in the biosynthesis of gangliosides, sialyl Lewis X antigens, and other important glycoconjugates, making it a target of interest in research related to cancer, immune response, and developmental biology.
Understanding the function of ST3GAL4 is essential for unraveling the complex mechanisms by which carbohydrate structures impact cellular processes and disease states. By utilizing the ST3GAL4 Polyclonal Antibody, researchers can gain valuable insights into the role of ST3GAL4 and its implications in various biological contexts.
Product Name:
ST3GAL4 Rabbit Polyclonal Antibody
SKU:
CAB6309
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-267 of human ST3GAL4 (NP_006269.1).
Golgi apparatus, Golgi stack membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
38kDa
Observed MW:
50-55kDa
This gene encodes a member of the glycosyltransferase 29 family, a group of enzymes involved in protein glycosylation. The encoded protein is targeted to Golgi membranes but may be proteolytically processed and secreted. The gene product may also be involved in the increased expression of sialyl Lewis X antigen seen in inflammatory responses. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6484
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse large intestine, using ST3GAL4 antibody (CAB6309) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
