The ST3GAL4 Polyclonal Antibody (CAB14491) is a valuable tool for researchers studying ST3GAL4, an enzyme involved in the biosynthesis of sialyl-Lewis x antigens. This antibody, raised in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the ST3GAL4 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in glycobiology and cancer research.ST3GAL4 is known for its role in the modification of glycoproteins and glycolipids, impacting various cellular processes such as cell adhesion and signaling.
Its involvement in the biosynthesis of sialyl-Lewis x antigens suggests a potential link to cancer progression and metastasis, making it a promising target for therapeutic interventions. Understanding the function of ST3GAL4 is crucial for unraveling its implications in disease pathology and developing targeted treatments for cancer and other related conditions.
Product Name:
ST3GAL4 Rabbit Polyclonal Antibody
SKU:
CAB14491
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 125-329 of human ST3GAL4 (NP_006269.1).
Golgi apparatus, Golgi stack membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
38kDa
Observed MW:
38kDa
This gene encodes a member of the glycosyltransferase 29 family, a group of enzymes involved in protein glycosylation. The encoded protein is targeted to Golgi membranes but may be proteolytically processed and secreted. The gene product may also be involved in the increased expression of sialyl Lewis X antigen seen in inflammatory responses. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6484
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using ST3GAL4 Rabbit pAb (CAB14491) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
