The ST3GAL4 Polyclonal Antibody (CAB13544) is a valuable tool for researchers studying ST3GAL4, an enzyme involved in the synthesis of sialyl-Lewis x antigens, which play a crucial role in cell adhesion and migration. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.ST3GAL4 is a key player in the regulation of cell surface glycosylation, impacting critical cellular processes such as cell-cell interactions, signaling, and immune responses. Dysregulation of ST3GAL4 has been implicated in various diseases, including cancer, inflammation, and autoimmune disorders.
By using the ST3GAL4 Polyclonal Antibody, researchers can investigate the expression levels and localization of ST3GAL4 in different cell types, providing valuable insights into its function and potential therapeutic targets.With its high specificity and sensitivity, the ST3GAL4 Polyclonal Antibody is an essential tool for studies in glycobiology, cancer biology, and immunology. By enabling precise detection and analysis of ST3GAL4 protein, this antibody contributes to the advancement of research in understanding the molecular mechanisms underlying disease pathogenesis and the development of targeted therapies.
Product Name:
ST3GAL4 Rabbit Polyclonal Antibody
SKU:
CAB13544
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-267 of human ST3GAL4 (NP_006269.1).
Golgi apparatus, Golgi stack membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
38kDa
Observed MW:
34-38kDa
This gene encodes a member of the glycosyltransferase 29 family, a group of enzymes involved in protein glycosylation. The encoded protein is targeted to Golgi membranes but may be proteolytically processed and secreted. The gene product may also be involved in the increased expression of sialyl Lewis X antigen seen in inflammatory responses. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6484
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ST3GAL4 antibody (CAB13544) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
