Description
ST14 Antibody (CAB6135)
The ST14 Antibody (CAB6135) is a high-quality antibody developed for reliable detection and analysis of target proteins. The ST14 Polyclonal Antibody (CAB6135) is specifically designed for researchers studying the function and regulation of ST14.This antibody, produced in rabbits, reacts strongly with human ST14 and has been validated for use in Western blot applications. By targeting the ST14 protein, researchers can accurately detect and analyze ST14 expression in different cell types, providing valuable insights into its role in various cellular processes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
| Product Name: | ST14 Antibody |
| SKU: | CAB6135 |
| Size: | 20μL, 100μL |
| Reactivity: | Human, Mouse |
| Conjugate: | Unconjugated |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | TCTK HTYR CLNG LCLS KGNP ECDG KEDC SDGS DEKD CDCG LRSF TRQA RVVG GTDA DEGE WPWQ VSLH ALGQ GHIC GASL ISPN WLVS AAHC YIDD RGFR YSDP TQWT AFLG LHDQ SQRS APGV QERR LKRI ISHP FFND FTFD YDIA LLEL EKPA EYSS MVRP ICLP DASH VFPA GKAI WVTG WGHT QYGG TGAL ILQK GEIR VINQ TTCE NLLP QQIT PRMM CVGF LSGG VDSC QGDS GGPL SSVE ADGR IFQA GVVS WGDG CAQR NKPG VYTR LPLF RDWI KENT GV | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | HAI, CAP3, MTSP1, SNC19, ARCI11, MT-SP1, PRSS14, TADG15, TMPRSS14, ST14 |
| Positive Sample: | THP-1, Mouse kidney, Mouse lung, Mouse liver |
| Cellular Localization: | Membrane, Single-Pass Type Ii Membrane Protein. |
| Calculated MW: | 95kDa |
| Observed MW: | 95kDa |
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
| Purification Method | Affinity purification |
| Gene ID | 6768 |
| RRID | AB_2766765 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
 | Western blot analysis of various lysates using ST14 Rabbit pAb (CAB6135) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s. |
