ST14 Rabbit Polyclonal Antibody (CAB6135)
- SKU:
- CAB6135
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ST14 Rabbit Polyclonal Antibody |
SKU: | CAB6135 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 566-855 of human ST14 (NP_068813.1). |
Sequence: | TCTK HTYR CLNG LCLS KGNP ECDG KEDC SDGS DEKD CDCG LRSF TRQA RVVG GTDA DEGE WPWQ VSLH ALGQ GHIC GASL ISPN WLVS AAHC YIDD RGFR YSDP TQWT AFLG LHDQ SQRS APGV QERR LKRI ISHP FFND FTFD YDIA LLEL EKPA EYSS MVRP ICLP DASH VFPA GKAI WVTG WGHT QYGG TGAL ILQK GEIR VINQ TTCE NLLP QQIT PRMM CVGF LSGG VDSC QGDS GGPL SSVE ADGR IFQA GVVS WGDG CAQR NKPG VYTR LPLF RDWI KENT GV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HAI; CAP3; MTSP1; SNC19; ARCI11; MT-SP1; PRSS14; TADG15; TMPRSS14; ST14 |
Positive Sample: | THP-1,Mouse kidney,Mouse lung,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type II membrane protein. |
Calculated MW: | 95kDa |
Observed MW: | 95kDa |
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Purification Method: | Affinity purification |
Gene ID: | 6768 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |