Hsc70-interacting protein (HIP) Rabbit Polyclonal Antibody (CAB8454)
- SKU:
- CAB8454
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Hsc70-interacting protein (HIP) Rabbit Polyclonal Antibody |
SKU: | CAB8454 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human Hsc70-interacting protein (HIP) (NP_003923.2). |
Sequence: | MDPR KVNE LRAF VKMC KQDP SVLH TEEM RFLR EWVE SMGG KVPP ATQK AKSE ENTK EEKP DSKK VEED LKAD EPSS EESD LEID KEGV IEPD TDAP QEMG DENA EITE EMMD QAND KKVA AIEA LNDG ELQK AIDL FTDA IKLN PRLA ILYA KRAS VFVK LQKP NAAI RDCD RAIE INPD SAQP YKWR GKAH RLLG HWEE AAHD LALA CKLD YDED ASAM LKEV QPRA QKIA EHRR KYER KREE REIK ERIE RVKK AREE HERA QREE EARR QSGA QYGS FPGG FPGG MPGN FPGG MPGM GGGM PGMA GMPG LNEI LSDP EVLA AMQD PEVM VAFQ DVAQ NPAN MSKY QSNP KVMN LISK LSAK FGGQ A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HIP; HOP; P48; AAG2; SNC6; HSPABP; FAM10A1; FAM10A4; HSPABP1; PRO0786; Hsc70-interacting protein (HIP) |
Positive Sample: | SW480,A-431,NIH/3T3,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 41kDa |
Observed MW: | 52kDa |
The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 6767 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |