The SSX5 Polyclonal Antibody (CAB7732) is a valuable tool for researchers studying the SSX5 protein, a member of the cancer/testis antigen family with implications in various cancers. This antibody, generated in rabbits, exhibits high reactivity with human samples and is optimized for Western blotting applications. By specifically binding to the SSX5 protein, this antibody enables the detection and analysis of SSX5 expression in different cell types, making it an ideal choice for investigations in oncology and cancer research.SSX5, a cancer/testis antigen, is known for its restricted expression in testis and various types of cancer, making it a promising target for cancer immunotherapy and biomarker discovery.
Understanding the role of SSX5 in cancer development and progression is crucial for identifying potential therapeutic strategies and diagnostic tools. The SSX5 Polyclonal Antibody provides researchers with a reliable tool to explore the functions and mechanisms of SSX5 in cancer biology, ultimately contributing to the advancement of cancer research and treatment.
Product Name:
SSX5 Rabbit Polyclonal Antibody
SKU:
CAB7732
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-229 of human SSX5 (NP_066295.3).
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
6758
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat liver, using SSX5 Rabbit pAb (CAB7732) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
