SSX4 Rabbit Polyclonal Antibody (CAB7929)
- SKU:
- CAB7929
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | SSX4 Rabbit Polyclonal Antibody |
SKU: | CAB7929 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-188 of human SSX4 (NP_005627.1). |
Sequence: | FMRS KRAA DFHG NDFG NDRN HRNQ VERP QMTF GSLQ RIFP KIMP KKPA EEEN GLKE VPEA SGPQ NDGK QLCP PGNP STLE KINK TSGP KRGK HAWT HRLR ERKQ LVVY EEIS DPEE DDE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CT5.4; SSX4 |
Positive Sample: | Mouse kidney,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | nucleus |
Calculated MW: | 22kDa |
Observed MW: | 27kDa |
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6759 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |