SSX2IP Antibody (PACO17155)
- SKU:
- PACO17155
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
SSX2IP Antibody (PACO17155)
The SSX2IP Polyclonal Antibody (PAC017155) is a valuable tool for researchers studying SSX2IP, a protein involved in various cellular processes, including mitosis and cell cycle progression. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By targeting the SSX2IP protein, this antibody enables precise detection and analysis in different cell types, making it an ideal choice for investigations in cell biology and cancer research.SSX2IP, also known as synovial sarcoma X breakpoint-interacting protein, plays a crucial role in the regulation of mitotic spindle assembly and chromosome segregation during cell division.
Dysregulation of SSX2IP has been associated with chromosomal instability and tumorigenesis, making it a promising target for studying cancer development and progression. By gaining insights into the function of SSX2IP, researchers can uncover potential therapeutic strategies for targeting cancer cells and improving treatment outcomes in cancer patients.
| Antibody Name: | SSX2IP Antibody (PACO17155) |
| Antibody SKU: | PACO17155 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:30-1:150 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human SSX2IP |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17155(SSX2IP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17155(SSX2IP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. |
| Synonyms: | synovial sarcoma, X breakpoint 2 interacting protein |
| UniProt Protein Function: | SSX2IP: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell adhesionChromosomal Location of Human Ortholog: 1p22.3Cellular Component: protein complex; cell-cell adherens junction; leading edge; nucleusMolecular Function: protein domain specific binding; protein bindingBiological Process: regulation of Rac protein signal transduction; centrosome organization and biogenesis; cilium biogenesis; cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q9Y2D8 |
| NCBI GenInfo Identifier: | 261878552 |
| NCBI Gene ID: | 117178 |
| NCBI Accession: | NP_001159889.1 |
| UniProt Secondary Accession: | Q9Y2D8,Q6P2P8, Q6ULS1, Q7L168, Q9UIX0, A8K8W0, B4DFE3 D3DT13, J3KR02 |
| UniProt Related Accession: | Q9Y2D8 |
| Molecular Weight: | 68,274 Da |
| NCBI Full Name: | afadin- and alpha-actinin-binding protein isoform 1 |
| NCBI Synonym Full Names: | synovial sarcoma, X breakpoint 2 interacting protein |
| NCBI Official Symbol: | SSX2IPÂ Â |
| NCBI Official Synonym Symbols: | ADIPÂ Â |
| NCBI Protein Information: | afadin- and alpha-actinin-binding protein; SSX2-interacting protein; afadin DIL domain-interacting protein |
| UniProt Protein Name: | Afadin- and alpha-actinin-binding protein |
| UniProt Synonym Protein Names: | Afadin DIL domain-interacting protein; SSX2-interacting protein |
| Protein Family: | Afadin- and alpha-actinin-binding protein |
| UniProt Gene Name: | SSX2IPÂ Â |
| UniProt Entry Name: | ADIP_HUMAN |
| Antibodies |
| SSX2IP Antibody (PACO12483) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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