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SSX2IP Antibody (PACO17154)

SKU:
PACO17154
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • SSX2IP Antibody PACO17154
  • SSX2IP Antibody PACO17154
  • SSX2IP Antibody PACO17154
€339
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Description

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SSX2IP Antibody (PACO17154)

The SSX2IP Polyclonal Antibody (PAC017154) is essential for research involving SSX2IP, a protein involved in chromosome segregation and cytokinesis. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SSX2IP protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent tool for studying cell division processes and their role in disease development.SSX2IP is crucial for proper chromosome segregation during cell division, ensuring the accurate distribution of genetic material to daughter cells.

Dysregulation of this process can lead to chromosomal instability, a hallmark of cancer development. Research on SSX2IP is essential for understanding the mechanisms underlying chromosome segregation errors and their contribution to tumorigenesis. By targeting SSX2IP, researchers can explore potential therapeutic strategies for treating cancer and other diseases related to cell division abnormalities.

Antibody Name:SSX2IP Antibody (PACO17154)
Antibody SKU:PACO17154
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:40-1:150
Species Reactivity:Human
Immunogen:Fusion protein of human SSX2IP
Form:Liquid
Storage Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:Antigen affinity purification
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageThe image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO17154(SSX2IP Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200).
Product ImageGel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hepg2 cells, Primary antibody: PACO17154(SSX2IP Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
Product ImageThe image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17154(SSX2IP Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200).
Background:This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.
Synonyms:synovial sarcoma, X breakpoint 2 interacting protein
UniProt Protein Function:SSX2IP: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell adhesionChromosomal Location of Human Ortholog: 1p22.3Cellular Component: protein complex; cell-cell adherens junction; leading edge; nucleusMolecular Function: protein domain specific binding; protein bindingBiological Process: regulation of Rac protein signal transduction; centrosome organization and biogenesis; cilium biogenesis; cell adhesion
UniProt Protein Details:
NCBI Summary:This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009]
UniProt Code:Q9Y2D8
NCBI GenInfo Identifier:261878552
NCBI Gene ID:117178
NCBI Accession:NP_001159889.1
UniProt Secondary Accession:Q9Y2D8,Q6P2P8, Q6ULS1, Q7L168, Q9UIX0, A8K8W0, B4DFE3 D3DT13, J3KR02
UniProt Related Accession:Q9Y2D8
Molecular Weight:68,274 Da
NCBI Full Name:afadin- and alpha-actinin-binding protein isoform 1
NCBI Synonym Full Names:synovial sarcoma, X breakpoint 2 interacting protein
NCBI Official Symbol:SSX2IP  
NCBI Official Synonym Symbols:ADIP  
NCBI Protein Information:afadin- and alpha-actinin-binding protein; SSX2-interacting protein; afadin DIL domain-interacting protein
UniProt Protein Name:Afadin- and alpha-actinin-binding protein
UniProt Synonym Protein Names:Afadin DIL domain-interacting protein; SSX2-interacting protein
Protein Family:Afadin- and alpha-actinin-binding protein
UniProt Gene Name:SSX2IP  
UniProt Entry Name:ADIP_HUMAN
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