The SSX2IP Polyclonal Antibody (PACO12483) is a valuable tool for researchers studying SSX2IP, a protein known to play a role in promoting tumor growth and metastasis. This antibody, produced in rabbits, has been extensively validated for use in various experimental applications, with a particular emphasis on its effectiveness in immunohistochemistry and Western blotting.SSX2IP, a member of the SSX2-interacting protein family, has been shown to interact with other proteins involved in cell cycle regulation and DNA repair processes, making it a potentially important target for cancer research.
By utilizing this antibody, researchers can accurately detect and analyze the expression of SSX2IP in different cell types and tissues, providing valuable insights into its function and potential as a therapeutic target for cancer treatment.The SSX2IP Polyclonal Antibody (PACO12483) is a versatile tool that can greatly enhance research efforts focused on understanding the role of SSX2IP in cancer biology, ultimately leading to the development of novel therapeutic strategies for combating this devastating disease.
synovial sarcoma, X breakpoint 2 interacting protein;SSX2IP;ADIP;FLJ10848;KIAA0923;MGC75026 ;
UniProt Protein Function:
SSX2IP: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell adhesionChromosomal Location of Human Ortholog: 1p22.3Cellular Component: protein complex; cell-cell adherens junction; leading edge; nucleusMolecular Function: protein domain specific binding; protein bindingBiological Process: regulation of Rac protein signal transduction; centrosome organization and biogenesis; cilium biogenesis; cell adhesion
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009]