The SSTR5 Rabbit Monoclonal Antibody (CAB8698) is a cutting-edge tool for studying somatostatin receptor 5 (SSTR5), a key player in the regulation of various physiological processes. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for researchers conducting Western blot analyses.SSTR5 is a G-protein coupled receptor known for its involvement in hormone secretion, neurotransmission, and cell proliferation. Its dysregulation has been linked to conditions such as neuroendocrine tumors and pituitary adenomas.
By targeting SSTR5 with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these diseases, paving the way for the development of targeted therapies.With its ability to detect and analyze SSTR5 in a variety of cell types, the SSTR5 Rabbit Monoclonal Antibody is a valuable tool for studies in endocrinology, oncology, and neurobiology. By elucidating the role of SSTR5 in different physiological contexts, researchers can uncover novel therapeutic strategies for a range of disorders associated with SSTR5 dysfunction.
Product Name:
SSTR5 Rabbit Monoclonal Antibody
SKU:
CAB8698
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SSTR5 (P35346).
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.
Purification Method:
Affinity purification
Gene ID:
6755
Clone Number:
ARC1282
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SSTR5 Rabbit mAb (CAB8698) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
