The Anti-Somatostatin (SST) Antibody (CAB20617) is a high-quality polyclonal antibody designed for research involving somatostatin, a hormone that regulates the endocrine system and neurotransmission. This antibody, raised in rabbits, exhibits high reactivity with somatostatin in human samples and is validated for use in various applications such as Western blotting.Somatostatin, also known as growth hormone-inhibiting hormone, plays a crucial role in regulating the secretion of several hormones, including growth hormone, insulin, and glucagon. Its involvement in the modulation of various physiological processes makes it a key target for research in endocrinology and neurobiology.
By binding to somatostatin, this antibody enables the detection and analysis of somatostatin in different tissues and cell types, making it suitable for studies related to hormone regulation and neuroendocrinology.Understanding the function and regulation of somatostatin is essential for advancements in medical research related to disorders such as acromegaly, diabetes, and neuroendocrine tumors. This antibody provides a valuable tool for researchers aiming to explore the role of somatostatin in various biological processes and potential therapeutic applications in the treatment of endocrine-related conditions.
Product Name:
Somatostatin (SST) Rabbit Monoclonal Antibody
SKU:
CAB20617
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-116 of human Somatostatin (SST) (NP_001039.1).
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.
Purification Method:
Affinity purification
Gene ID:
6750
Clone Number:
ARC50670
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of Somatostatin (SST) in paraffin-embedded mouse pancreas tissue using Somatostatin (SST) Rabbit mAb (CAB20617) at a dilution of 1:500 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
