The SSR4 Polyclonal Antibody (CAB8037) is a valuable tool for researchers studying SSR4, a protein involved in mitochondrial protein import and biogenesis. This antibody, created using rabbit polyclonal antibodies, is highly specific for human samples and has been validated for use in Western blot applications. It binds to the SSR4 protein, allowing for detection and analysis in various cell types, making it ideal for studies in mitochondrial biology and related diseases.
SSR4 is essential for proper functioning of the mitochondria, the powerhouse of the cell, and plays a crucial role in maintaining cellular energy production. Dysregulation of SSR4 has been linked to various mitochondrial disorders and diseases, making it a promising target for therapeutic interventions. Understanding the function and regulation of SSR4 is essential for developing strategies to treat mitochondrial-related diseases and improve overall cellular health.
Product Name:
SSR4 Rabbit Polyclonal Antibody
SKU:
CAB8037
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-144 of human SSR4 (NP_006271.1).
Endoplasmic reticulum membrane, Single-pass type I membrane protein.
Calculated MW:
19kDa
Observed MW:
19kDa
This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6748
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SSR4 antibody (CAB8037) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
