The SS18L2 Antibody (PAC012471) is a high-quality polyclonal antibody designed for research involving the SS18L2 protein. This protein is known to play a role in chromatin remodeling and gene regulation, making it a key player in various cellular processes. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in various applications, including Western blotting. It specifically binds to the SS18L2 protein, allowing for its detection and analysis in different cell types.
The SS18L2 protein is implicated in cancer development and progression, making it an important target for cancer research. By studying and understanding the role of SS18L2, researchers can gain insights into the mechanisms underlying cancer growth and potentially develop targeted therapies.Overall, the SS18L2 Antibody is a valuable tool for researchers looking to delve into the functions and implications of the SS18L2 protein in cancer and other cellular processes.
synovial sarcoma translocation gene on chromosome 18-like 2;SS18L2;KIAA-iso ;
UniProt Protein Function:
SS18L2: Belongs to the SS18 familyChromosomal Location of Human Ortholog: 3p21
UniProt Protein Details:
NCBI Summary:
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L2 gene is homologous to SS18.[supplied by OMIM, Jul 2002]
